Radiology

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The is article focuses on radiology as a medical specialty. See also medical imaging.
For industrial application see Radiography.
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Meeting protocol of the Würzburg Physical-Medical Society in the 1895 volume.
Examination of an X-ray exposure of a patient

Radiology is the branch or speciality of medicine that deals with the study and application of imaging technology like x-ray and radiation to diagnosing and treating disease.

Originally it was the aspect of medical science dealing with the use of electromagnetic energy emitted by X-ray machines or other such radiation devices for the purpose of obtaining visual information as part of medical imaging. Radiology that involves use of x-ray is called roentgenology. The modern day radiological imaging is no longer limited to the use of x-rays, and now includes technology-intensive imaging with high frequency sound waves, magnetic fields, and radioactivity.

Wilhelm Conrad Röntgen (English spelling Roentgen) first discovered x-radiation on 8 November 1895 at the Physical Institute of Würzburg University.[1] He named the radiation he had discovered "X-radiation". This term is still in use today in the Anglo-American region. His work was first published in a meeting protocol of the Würzburg Physical-Medical Society in the 1895 volume; the article was submitted by W.C. Röntgen on 28 December 1895. Roentgen received the first Nobel Prize for Physics for the discovery of X-rays in 1901.

Today, following extensive training, radiologists direct an array of imaging technologies (such as ultrasound, computed tomography (CT) Computer Assisted Tomography, nuclear medicine, Positron Emission Tomography (PET) and magnetic resonance imaging (MRI)) to diagnose or treat disease. Interventional radiology is the performance of (usually minimally invasive) medical procedures with the guidance of imaging technologies. The acquisition of medical imaging is usually carried out by the radiographer or radiologic technologist. Outside of the medical field, radiology also encompasses the examination of the inner structure of objects using X-rays or other penetrating radiation.


Contents

[edit] Acquisition of radiological images

The following imaging modalities are used in the field of diagnostic radiology:

[edit] Projection (plain) radiography

Main article: Projectional radiography

Radiographs (or Roentgenographs, named after the discoverer of X-rays, Wilhelm Conrad Röntgen (1845–1923))[2]:1 are often used for evaluation of bony structures and soft tissues. An X-Ray machine directs electromagnetic radiation upon a specified region in the body. This radiation tends to pass through less dense matter (air, fat, muscle, and other tissues), but is absorbed or scattered by denser materials (bones, tumors, lungs affected by severe pneumonia). In Film-Screen Radiography, radiation which has passed through a patient then strikes a cassette containing a screen of fluorescent phosphors and exposes x-ray film. Areas of film exposed to higher amounts of radiation will appear as black or grey on X-ray film while areas exposed to less radiation will appear lighter or white. In Computed Radiography (CR), the x-rays passing through the patient strike a sensitized plate which is then read and digitized into a computer image by a separate machine. In Digital Radiography the x-rays strike a plate of x-ray sensors producing a digital computer image directly. While all three methods are currently in use, the trend in the U.S. is away from film and toward digital imaging.

Plain radiography was the only imaging modality available during the first 50 years of Radiology. It is still the first study ordered in evaluation of the lungs, heart and skeleton because of its wide availability, speed and relative low cost.

[edit] Fluoroscopy

Main article: Fluoroscopy

Fluoroscopy and angiography are special applications of X-ray imaging, in which a fluorescent screen or image intensifier tube is connected to a closed-circuit television system.[2]:26 This allows real-time imaging of structures in motion or augmented with a radiocontrast agent. Radiocontrast agents are administered, often swallowed or injected into the body of the patient, to delineate anatomy and functioning of the blood vessels, the genitourinary system or the gastrointestinal tract. Two radiocontrasts are presently in use. Barium (as BaSO4) may be given orally or rectally for evaluation of the GI tract. Iodine, in multiple proprietary forms, may be given by oral, rectal, intraarterial or intravenous routes. These radiocontrast agents strongly absorb or scatter X-ray radiation, and in conjunction with the real-time imaging allows demonstration of dynamic processes, such as peristalsis in the digestive tract or blood flow in arteries and veins. Iodine contrast may also be concentrated in abnormal areas more or less than in normal tissues and make abnormalities (tumors, cysts, inflammation) more conspicuous. Additionally, in specific circumstances air can be used as a contrast agent for the gastrointestinal system and carbon dioxide can be used as a contrast agent in the venous system; in these cases, the contrast agent attenuates the X-ray radiation less than the surrounding tissues.

[edit] CT scanning

Main article: Computed tomography

CT imaging uses X-rays in conjunction with computing algorithms to image the body. In CT, an X-ray generating tube opposite an X-ray detector (or detectors) in a ring shaped apparatus rotate around a patient producing a computer generated cross-sectional image (tomogram). CT is acquired in the axial plane, while coronal and sagittal images can be rendered by computer reconstruction. Radiocontrast agents are often used with CT for enhanced delineation of anatomy. Intravenous contrast can allow 3D reconstructions of arteries and veins. Although radiographs provide higher spatial resolution, CT can detect more subtle variations in attenuation of X-rays. CT exposes the patient to more ionizing radiation than a radiograph. Spiral Multi-detector CT utilizes 8,16 or 64 detectors during continuous motion of the patient through the radiation beam to obtain much finer detail images in a shorter exam time. With computer manipulation these images can be reconstructed into 3D images of carotid, cerebral and coronary arteries. CT scanning has become the test of choice in diagnosing some urgent and emergent conditions such as cerebral hemorrhage, pulmonary embolism (clots in the arteries of the lungs), aortic dissection (tearing of the aortic wall), appendicitis, diverticulitis, and obstructing kidney stones. Continuing improvements in CT technology including faster scanning times and improved resolution have dramatically increased the accuracy and usefulness of CT scanning and consequently increased utilization in medical diagnosis.

The first commercially viable CT scanner was invented by Sir Godfrey Hounsfield at EMI Central Research Labs, Great Britain in 1972. EMI owned the distribution rights to The Beatles music and it was their profits which funded the research. Sir Hounsfield and Alan McLeod McCormick shared the Nobel Prize for Medicine in 1979 for the invention of CT scanning. The first CT scanner in North America was installed at the Mayo Clinic in Rochester, MN in 1972.

[edit] Ultrasound

Main article: Ultrasound

Medical ultrasonography uses ultrasound (high-frequency sound waves) to visualize soft tissue structures in the body in real time. No ionizing radiation is involved, but the quality of the images obtained using ultrasound is highly dependent on the skill of the person (ultrasonographer) performing the exam. Ultrasound is also limited by its inability to image through air (lungs, bowel loops) or bone. The use of ultrasound in medical imaging has developed mostly within the last 30 years. The first ultrasound images were static and two dimensional (2D), but with modern-day ultrasonography 3D reconstructions can be observed in real-time; effectively becoming 4D.

Because ultrasound does not utilize ionizing radiation, unlike radiography, CT scans, and nuclear medicine imaging techniques, it is generally considered safer. For this reason, this modality plays a vital role in obstetrical imaging. Fetal anatomic development can be thoroughly evaluated allowing early diagnosis of many fetal anomalies. Growth can be assessed over time, important in patients with chronic disease or gestation-induced disease, and in multiple gestations (twins, triplets etc.). Color-Flow Doppler Ultrasound measures the severity of peripheral vascular disease and is used by Cardiology for dynamic evaluation of the heart, heart valves and major vessels. Stenosis of the carotid arteries can presage cerebral infarcts (strokes). DVT in the legs can be found via ultrasound before it dislodges and travels to the lungs (pulmonary embolism), which can be fatal if left untreated. Ultrasound is useful for image-guided interventions like biopsies and drainages such as thoracentesis). It is also used in the treatment of kidney stones (renal lithiasis) via lithotripsy. Small portable ultrasound devices now replace peritoneal lavage in the triage of trauma victims by directly assessing for the presence of hemorrhage in the peritoneum and the integrity of the major viscera including the liver, spleen and kidneys. Extensive hemoperitoneum (bleeding inside the body cavity) or injury to the major organs may require emergent surgical exploration and repair.

[edit] MRI (Magnetic Resonance Imaging)

Main article: Magnetic resonance imaging

MR image of human knee

MRI uses strong magnetic fields to align atomic nuclei (usually hydrogen protons) within body tissues, then uses a radio signal to disturb the axis of rotation of these nuclei and observes the radio frequency signal generated as the nuclei return to their baseline states plus all surrounding areas. The radio signals are collected by small antennae, called coils, placed near the area of interest. An advantage of MRI is its ability to produce images in axial, coronal, sagittal and multiple oblique planes with equal ease. MRI scans give the best soft tissue contrast of all the imaging modalities. With advances in scanning speed and spatial resolution, and improvements in computer 3D algorithms and hardware, MRI has become an essential tool in musculoskeletal radiology and neuroradiology.

One disadvantage is that the patient has to hold still for long periods of time in a noisy, cramped space while the imaging is performed. Claustrophobia severe enough to terminate the MRI exam is reported in up to 5% of patients. Recent improvements in magnet design including stronger magnetic fields (3 teslas), shortening exam times, wider, shorter magnet bores and more open magnet designs, have brought some relief for claustrophobic patients. However, in magnets of equal field strength there is often a trade-off between image quality and open design. MRI has great benefit in imaging the brain, spine, and musculoskeletal system. The modality is currently contraindicated for patients with pacemakers, cochlear implants, some indwelling medication pumps, certain types of cerebral aneurysm clips, metal fragments in the eyes and some metallic hardware due to the powerful magnetic fields and strong fluctuating radio signals the body is exposed to. Areas of potential advancement include functional imaging, cardiovascular MRI, as well as MR image guided therapy.

[edit] Nuclear Medicine

Main article: Nuclear medicine

Nuclear medicine imaging involves the administration into the patient of radiopharmaceuticals consisting of substances with affinity for certain body tissues labeled with radioactive tracer. The most commonly used tracers are Technetium-99m, Iodine-123, Iodine-131, Gallium-67 and Thallium-201. The heart, lungs, thyroid, liver, gallbladder, and bones are commonly evaluated for particular conditions using these techniques. While anatomical detail is limited in these studies, nuclear medicine is useful in displaying physiological function. The excretory function of the kidneys, iodine concentrating ability of the thyroid, blood flow to heart muscle, etc. can be measured. The principal imaging device is the gamma camera which detects the radiation emitted by the tracer in the body and displays it as an image. With computer processing, the information can be displayed as axial, coronal and sagittal images (SPECT images). In the most modern devices Nuclear Medicine images can be fused with a CT scan taken quasi-simultaneously so that the physiological information can be overlaid or co-registered with the anatomical structures to improve diagnostic accuracy.

PET scanning also falls under "nuclear medicine." In PET scanning, a radioactive biologically-active substance, most often Fluorine-18 Fluorodeoxyglucose, is injected into a patient and the radiation emitted by the patient is detected to produce multi-planar images of the body. Metabolically more active tissues, such as cancer, concentrate the active substance more than normal tissues. PET images can be combined with CT images to improve diagnostic accuracy.

The applications of nuclear medicine can include bone scanning which traditionally has had a strong role in the work-up/staging of cancers. Myocardial perfusion imaging is a sensitive and specific screening exam for reversible myocardial ischemia. Molecular Imaging is the new and exciting frontier in this field.

[edit] Teleradiology

Teleradiology is the transmission of radiographic images from one location to another for interpretation by a radiologist. It is most often used to allow rapid interpretation of emergency room, ICU and other emergent examinations after hours of usual operation, at night and on weekends. In these cases the images are often sent across time zones,(Spain, Australia,India) with the receiving radiologist working his normal daylight hours. Teleradiology can also be utilized to obtain consultation with an expert or sub-specialist about a complicated or puzzling case.

Teleradiology requires a sending station, high speed Internet connection and high quality receiving station. At the sending station, plain radiographs are passed through a digitizing machine before transmission, while CT scans, MRIs, Ultrasounds and Nuclear Medicine scans can be sent directly as they are already a stream of digital data. The computer at the receiving end will need to have a high-quality display screen that has been tested and cleared for clinical purposes. The interpreting radiologist will then fax or e-mail the radiology report to the requesting physician.

The major advantage of teleradiology is the ability to utilize different time zones to provide real-time emergency radiology services around-the-clock. The disadvantages include higher costs , limited contact between the ordering physician and the radiologist, and the inability to cover for procedures requiring an onsite radiologist. Laws and regulations concerning the use of teleradiology vary among the states, with some states requiring a license to practice medicine in the state sending the radiologic exam. Some states require the teleradiology report to be preliminary with the official report issued by a hospital staff radiologist.

[edit] Radiologist training

 The examples and perspective in this section may not represent a worldwide view of the subject. Please improve this article or discuss the issue on the talk page.

[edit] United States

Diagnostic radiologists must complete prerequisite undergraduate training, four years of medical school, and five years of post-graduate training. The first postgraduate year is usually a transitional year of various rotations, but is sometimes a preliminary internship in medicine or surgery. A four-year diagnostic radiology residency follows. During this residency, the radiology resident must pass a medical physics board exam covering the science and technology of ultrasounds, CTs, x-rays, nuclear medicine, and MRI. Core knowledge of the radiologist includes radiobiology which is the study of the effects of ionizing radiation on living tissue. Near the completion of their residency, the radiologist in training is eligible to take board examinations (written and oral) given by the American Board of Radiology (ABR). Starting in 2010 though, the ABR will be changing the board examination structure to two computer-based exams, one given after the third year of residency training, and the second given 18 months after the first. [3]

Following completion of residency training, radiologists either begin their practice or enter into sub-speciality training programs known as fellowships. Examples of sub-speciality training in radiology include abdominal imaging, thoracic imaging, CT/Ultrasound, MRI, musculoskeletal imaging, interventional radiology, neuroradiology, interventional neuroradiology, pediatric radiology, mammography and women's imaging. Fellowship training programs in radiology are usually 1 or 2 years in length.

Radiologists generally achieve a higher level of compensation than many medical specialties as well as a highly desirable regular work schedule that often does not involve many weekend or night hours. The introduction of teleradiology has significantly improved the working environment and schedules of radiologists, essentially distributing the increasing workflow into shifts. Those seeking residency positions find that entry into this field of medicine is highly competitive. The field is rapidly expanding due to advances in computer technology which is closely linked to modern imaging. The exams (radiography) are usually performed by radiologic technologists, (also known as diagnostic radiographers) who in the United States have a 2-year Associates Degree and the UK a 3 year Honours Degree.

Veterinary radiologists are veterinarians that specialize in the use of X-rays, ultrasound, MRI and nuclear medicine for diagnostic imaging or treatment of disease in animals. Veterinary radiologists are certified in either diagnostic radiology or radiation oncology by the American College of Veterinary Radiology.

[edit] Germany

After earning the right to practice medicine, German physicians who want to be a radiologist have to go through a 5-year residency, ending with a board examination(Facharztausbildung). During this time, physicians are educated in all aspects of their chosen field of medicine. Usually this includes rotations serving...

[edit] References

  1. ^ P. Thurn, E. Bücheler: Einführung in die radiologische Diagnostik, Stuttgart: Thieme, 8. Aufl. 1986
  2. ^ a b Novelline, Robert. Squire's Fundamentals of Radiology. Harvard University Press. 5th edition. 1997. ISBN 0674833392.
  3. ^ How To Become A Radiologist

[edit] See also

  • Antoine Béclère, virologist and immunologist, a pioneer in radiology
  • C-Arm, equipment that uses x-rays to produce an image feed displayed on a TV screen
  • Interventional radiology, in which minimally invasive procedures are performed using image guidance
  • Medical radiography, the use of ionizing electromagnetic radiation, such as X-rays, in medicine
  • Mumoli's sign, a rabbit-shaped image seen on ultrasound of the liver
  • Positron emission tomography, which produces a three-dimensional image
  • Radiobiology, the interdisciplinary science that studies the biological effects of ionizing and non-ionizing radiation of the whole electromagnetic spectrum
  • Radiation protection, the science of protecting people and the environment from the harmful effects of ionizing radiation
  • Radiography, the use of X-rays to view unseen or hard-to-image objects
  • Radiosensitivity, the susceptibility of organic tissues to the harmful effect of ionizing radiation
  • Teleradiology, the transmission by electronic means of radiological patient images from one location to another for interpretation or consultation

[edit] External links

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